The Department of Moral Theology offers licentiate and canonical doctorate programs in Moral Theology. The central axis of the curriculum concerns the study of the sources of moral discernment: Sacred Scripture, Tradition, current Church teaching, dialogue with secular culture and other religious traditions, consciousness and group analysis of some cases. Other topics include the history of Moral Theology, Social Ethics, Ethics of the Person, and dialogue with contemporary culture.

Students are stimulated to make a formative journey of study of the sources and research open to today's world and its challenges, of critical reflection in faithfulness to the Magisterium of the Church. Each student is invited to have a personal relationship with his or her professors and to exchange ideas with other students of different origins. The Pontifical Gregorian University, in fact, is a place where students experience the universality of the Church and the world today, and offers the possibility of interdisciplinary dialogue with professors and students from other specializations of Theology and other faculties and institutes.

Studying Moral Theology at a university such as the Pontifical Gregorian University offers a wide range of choices among a number of ancillary specializations (Diploma in Practical Theology with specialization in Family Ministry, Joint Diploma in Integral Ecology, Diploma in Safeguarding of Minors from the Institute of Psychology), as well as the possibility of pursuing a number of special interests. With its six faculties, multiple centers and institutes integrated into the "Gregorian Consortium" (which also includes the Pontifical Biblical Institute and the Pontifical Oriental Institute), the Pontifical Gregorian University is particularly well suited to allow anyone to personalize their studies, following the Jesuit pedagogical tradition that emphasizes "cura personalis".